2-O-tert-Butyldimethylsilyl-4,6-O-ethylidene-myo-insitol 1,3,5-orthoformate
نویسندگان
چکیده
In the title compound, C(15)H(26)O(6)Si, the dioxa six-membered ring bonded to the myo-inositol skeleton is in a boat conformation while the rest of the six-membered rings adopt chair conformations.
منابع مشابه
Exciplex and excimer molecular probes: detection of conformational flip in a myo-inositol chair.
2-O-tert-Butyldimethylsilyl-4,6-bis-O-pyrenoyl-myo-inositol-1,3,5-orthoformate (6) and 2-O-tert-butyldimethylsilyl-4-O-[4-(dimethylamino)benzoyl]-6-O-pyrenoyl-myo-inositol-1,3,5-orthoacetate (10) adopt conformationally restricted unstable chairs with five axial substituents. In the symmetrical diester 6, the two pi-stacked pyrenoyl groups are electron acceptor-donor partners, giving a strong in...
متن کاملMetal trifluoromethanesulfonate-catalyzed regioselective acylation of myo-inositol 1,3,5-orthoformate.
A highly regioselective acylation of myo-inositol 1,3,5-orthoformate at the 4-O/6-O positions is catalyzed by various metal trifluoromethanesulfonates, giving excellent yields; an asymmetric example using (-)-camphanic anhydride is described here.
متن کاملRegioselective Opening of myo-Inositol Orthoesters: Mechanism and Synthetic Utility
Acid hydrolysis of myo-inositol 1,3,5-orthoesters, apart from orthoformates, exclusively affords the corresponding 2-O-acyl myo-inositol products via a 1,2-bridged five-membered ring dioxolanylium ion intermediate observed by NMR spectroscopy. These C-2-substituted inositol derivatives provide valuable precursors for rapid and highly efficient routes to 2-O-acyl inositol 1,3,4,5,6-pentakisphosp...
متن کاملO-(tert-Butyldimethylsilyl)tris(O-4-methylphenylsulfonyl)pentaerythritol
IN THE TITLE COMPOUND [SYSTEMATIC NAME: (tert-butyl-dimethyl-silyl)methane-triyl tris-(4-methyl-benzene-sulfonate)], C(32)H(44)O(10)S(3)Si, the central C atom and the Si(IV) center are in a tetra-hedral configuration. The inter-planar angles between pairs of the three benzene rings of the 4-methyl-phenyl-sulfonyl units are 41.15 (10), 18.11 (10) and 44.09 (10)°. C-H⋯π inter-actions are observed...
متن کاملN 2,N 2,N 4,N 4-Tetraethyl-6-{2-[(E)-1-(4-nitrophenyl)ethylidene]hydrazino}-1,3,5-triazine-2,4-diamine
The title compound, C(19)H(28)N(8)O(2), was prepared by the reaction of N(2),N(2),N(4),N(4)-tetra-ethyl-6-hydrazino-1,3,5-triazine-2,4-diamine and 1-(4-nitro-phen-yl)ethanone in ethanol at room temperature. The mol-ecular conformation is stabilized by intra-molecular C-H⋯N hydrogen-bonding inter-actions. There are also inter-molecular N-H⋯O hydrogen bonds, and C-H⋯π and π-π inter-actions, which...
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